Dr. Mickey A. Latour : B.S. Southeastern Louisiana University; M.S. and Ph.D., Mississippi State University and National Institutes of Health (NIH) Postdoctoral Fellow at Washington University School of Medicine, Department of Internal Medicine, Division of Atherosclerosis, Nutrition and Lipid Research.
  • Research in my laboratory is centered around lipid transfer in chicks from hens at various stages of production. Presently, we are using a state-of-the-art kinetic techniques which allows us to monitor precisely the differences exhibited in egg parameters between different aged flocks and species.
  • Our goal will be to understand the compromised physiology/biochemistry associated with chicks from various aged hens when incubated under similar conditions. These studies are designed to investigate various aspects of lipid metabolism, which are known to be compromised in newly hatched chicks from different aged hens. We have found that chicks from young hens have higher than expected levels of total cholesterol, low density lipoprotein (LDL) and high density lipoprotein (HDL) cholesterol when compared to chicks from older hens. This suggests that the metabolism of lipoproteins may be compromised in chicks from young hens. To understand what occurs in circulation, we will investigate the in vivo metabolism of specific apolipoproteins and their particles in the newly hatched chicks from different aged hens.
  • Other research interests include: A) Stress Effects On Lipoproteins; B) Fatty Acid Turnover Studies Using RadioactiveTracers; C) Protein Turnover Studies Using Stable Isotopes;  D) Atherosclerosis and E) Animal Behavior.

 

Original Journal Articles:

1)            Brake*, J.D., M.J. Fuller*, C.R. Boyle, D.E. Link*, E.D. Peebles* and M.A. Latour*. 1993. Evaluations of whole chopped Kenef and Kenef core used as broiler litter material. Poultry Sci. 72:2079-2083.

2)            Pugh*, C.R., E.D. Peebles*, N.P. Pugh* and M.A. Latour*. 1993. Ultrasonography as a tool for monitoring in ovo chicken development. 1. Technique and morphological findings. Poultry Sci. 72:2236-2246.

3)            Peebles*, E.D., C.R. Pugh*, C.R. Boyle, M.A. Latour*, N.P. Pugh and J.D. Brake. 1993. Ultrasonography as a tool for monitoring in ovo chicken development. 2. Effects of eggshell alteration and ultrasonography on embryonic and posthatch development. Poultry Sci. 72:2247-2253.

4)            Peebles*, E.D., E.H. Miller*, C.R. Boyle*, J.D. Brake and M.A. Latour*.  1994. Effect of dietary thiouracil on thyroid activity, egg production, and eggshell quality in commercial layers. Poultry Sci. 73:1829-1837.

5)            Latour*, M.A., E.D. Peebles* and J.D. Brake*.  1994.  The effects of dietary fat on growth performance, carcass composition, and feed efficiency in the broiler chick. Poultry Sci. 73:1362-1369.

6)            Latour*, M.A, E.D. Peebles*, C.R. Boyle, J.D. Brake and T.F. Kellogg.  1995. Changes in serum lipid, lipoprotein and corticosterone concentrations during neonatal chick development. Biology of the Neonate 67:381-386.

7)            Branton*, S.L., B.D. Lott, J.D. May*, P.A. Hedin, F.W. Austin*, M.A. Latour* and E.J. Day.  1996. The effects of nonautoclaved and autoclaved water-soluble wheat extracts on the growth of Clostridium perfringens. Poultry Sci. 75:335­-338.

8)            Latour*, M.A., E.D. Peebles*, C.R. Boyle, S.M. Doyle, T. Pansky and J.D. Brake.  1996. Effects of breeder hen age and dietary fat on embryonic and neonatal broiler serum lipids and glucose. Poultry Sci. 75:695-701.

9)            Latour*, M.A., S.A. Laiche*, J.R. Thompson*, A.L. Pond and E.D. Peebles.  1996. Continuous infusion of adrenocorticotropin influences circulating lipoproteins and corticosterone concentrations in chickens. Poultry Sci. 75: 1428-1432.

10)        Peebles*, E.D., J.D. Cheaney*, K. Vaughn*, M.A. Latour*, T.W. Smith, R.L. Haynes and C.R. Boyle.  1996. Changes in gonadal weights, serum lipids and glucose during maturation in the juvenile Northern Bobwhite quail (Colinus virginianus). Poultry Sci. 75:1411-1416.

11)        Srivastava*, N., D. Noto*, M. Averna, J. Pulai* R.A. Srivastavsa, T.G. Cole, M.A. Latour*, B.W. Patterson* and G. Schonfeld.  1996. A new apolipoprotein B truncation (apoB-43.7) in familial hypobetalipoproteinemia: Genetic and metabolic studies. Metabolism:  Experimental and Clinical 45(10) 1296-1304.

12)        Peebles*, E.D., M.A. Latour*, S.E. Broome*, J.D. Cheaney* and C.D. Zumwalt.  1996.  Effects of oral ethanol on serum lipoprotein cholesterol in juvenile meat-type chickens.  Alcohol 13:111-115

13)        Shaish*, A., M. Pape*, T. Rea*, R.K.A. Srivastava, M.A. Latour* and G. Schonfeld.  1997. Alcohol increases diet-induced atherogenic lipoproteins and aortic atherosclerosis in rabbits. Arteriosclerosis, Thrombosis and Vascular Biology 17:1091-1097.

14)        Branton*, S.L., B.D. Lott, J.W. Deaton*, W.R. Maslin*, F.W. Austin, L. Pote, R.W. Keirs, M.A. Latour* and E.J. Day.  1997. The effect of added complex carbohydrates or added dietary fiber on necrotic enteritis lesions in broiler chickens. Poultry Sci. 76:24-28.

15)        Peebles*, E.D., J.D. Cheaney*, J.D. Brake, C.R. Boyle and M.A. Latour*.  1997. Effects of added dietary lard on body weight, and serum glucose and low density lipoprotein cholesterol in random bred broiler chickens. Poultry Sci. 76:29-36.

16)        Latour*, M.A., B.W. Patterson*, J. Pulai, Z. Chen and G. Schonfeld.  1997. Metabolism of apolipoprotein B-100 in hypobetalipoproteinemia (FHBL) subjects differs among kindreds with known and unknown defects. Journal of Lipid Research 38:592-599.

17)        Peebles*, E.D., E.H. Miller*, C.R. Boyle, J.D. Brake*, M.A. Latour* and J.P. Thaxton.  1997. Effects of consecutive thiourcil exposures in the juvenile and adult single comb White Leghorn chicken on body weight and reproductive performance. Poultry Sci. 76:236-243.

18)        Peebles* E.D., A.L. Pond*, J.R. Thompson*, C.D. McDaniel, N.M. Cox and M.A. Latour*.  1997. Naloxone attenuates serum corticosterone and augments serum glucose concentrations in ACTH-stimulated broilers. Poultry Sci. 76:511-515.

19)        Puradolpirod*, S., J.R. Thompson*, J. Green, M.A. Latour* and J.P. Thaxton*. 1997. Influence of the yolk on blood metabolites in perinatal and neonatal chickens Growth, Development, and Aging 61:39-45.

20)        Pulai*, J., M. Averna* R.A.K. Srivastava, M.A. Latour* R.E. Clouse* and G. Schonfeld.  1997. Normal intestinal dietary fat and cholesterol absorption, intestinal apolipoproteinB (apoB) mRNA levels, and ApoB-48 synthesis in a hypobeta-lipoproteinemic kindred without any ApoB truncation. Metabolism: Clinical and Experimental 46:1095-1100.

21)        Peebles*, E.D., J.D. Cheaney*, J.D. Brake*, C.R. Boyle, M.A. Latour* and C.D. McDaniel.  1997. Effects of added lard fed to broiler chickens during the starter phase. II. Serum lipids. Poultry Sci. 76:1648-1654.

22)        Peebles*, E.D., J.D. Brake* and M.A. Latour*.  1997. Broiler performance, yield, and bone characteristics as affected by starter diet fat levels. Journal of Applied Poultry Research 6:325-330.

23)        Peebles*, E.D., J.D. Cheaney*, J.D. Brake*, C.R. Boyle, M.A. Latour* and C.D. McDaniel.  1997. Effects of added dietary lard fed to broiler chickens during the starter phase. I. Body and selected organ weights, feed conversion, hematology, and serum glucose. Poultry Sci. 76:1641-1647.

24)        Latour*, M.A., E.D. Peebles*, C.W. Gardner* and G. Schonfeld.  1997. An evaluation of the lipoprotein composition and corresponding apolipoproteins in the newly hatched male and female broiler chick from two different age flocks. Biology of the Neonate 72:380-388.

25)        Latour*, M.A., E.D. Peebles*, S.M. Doyle*, T. Pansky*, T.W. Smith and C.R. Boyle.  1998. Breeder age and dietary fat influence yolk fatty acid profiles of fresh eggs and newly hatched chicks. Poultry Sci. 77:47-53.

26)        Peebles*, E.D., T. Pansky*, S.M. Doyle*, C.R. Boyle, T.W. Smith, M.A. Latour* and P.D. Gerrard*. 1998. Effects of dietary fat and eggshell cuticle removal on egg water loss and embryo growth in broiler hatching eggs. Poultry Sci. 77:1522-1530.

27)        Latour*, M.A., D. Hopkins*, T. Kitchens* and G. Schonfeld.  1998. Effects of feeding a liquid diet for one year to New Zealand White rabbits. Laboratory Animal Science 48:81-84.

28)        Pulai*, J.I., M.A. Latour*, P. Kwok* and G. Schonfeld.  1998. Diabetes mellitus in a new kindred with familial hypobetalipoproteinemia and an apolipoprotein B truncation (apoB-55). Atherosclerosis 136:289-295.

29)        Peebles*, E.D., T. Pansky*, S.M. Doyle*, T.W. Smith*, C.R. Boyle*, M.A. Latour* and P.D. Gerrard*. 1998. Effects of breeder dietary fat and eggshell cuticle removal on subsequent broiler growout performance. J. Appl. Poultry Res. 7:377-383.

30)        Peebles*, E.D., S.M. Doyle*, T. Pansky*, P.D. Gerrard*, M.A. Latour*, C.R. Boyle, and T.W. Smith*.  1999. Effects of breeder age and dietary fat on subsequent broiler performance. 1. Growth, mortality, and feed conversion. Poultry Sci. 78: 505-511.

31)        Peebles*, E.D, S.M. Doyle*, T. Pansky*, P.D. Gerrard*, M.A. Latour*, C.R. Boyle and T.W. Smith*.  1999. Effects of breeder age and dietary fat on subsequent broiler performance. 2. Slaughter Yield. Poultry Sci. 78:512-515.

32)        Latour*, M.A., B. Patterson*, T. Kitchens*, R.E. Ostlund*, D. Hopkins and G. Schonfeld*.  1999. Effects of alcohol and cholesterol feeding on lipoprotein metabolism and cholesterol absorption in rabbits. Arteriosclerosis, Thrombosis and Vascular Biology 19:598-604.

33)        Frank*, N., J.E. Sojka*, M.A. Latour*, S.R. McClure* and L. Polazzi*.  1999. Effect of hypothyroidism on the blood lipid concentrations in horses. Amer. J. Vet. Res. 60:730-733.

34)        Chen*, Z., J.E. Saffitz*, M.A. Latour*, and G. Schonfeld*.  1999. Truncated apoB-70.5-containing lipoproteins bind to megalin but not the LDL receptor. J. Clin. Investigation 103:1419-1430.

35)        Peebles*, E.D., L.M. Li*, S. Miller*, T. Pansky* S. Whitmarsh*, M.A. Latour* and P.D. Gerrard*.  1999.  Embryo and yolk compositional relationships in broiler hatching eggs during incubation.  Poultry Sci. 78:1435-1442.

36)        Latour*, M.A., R.A. Meunier*, A.A. Devitt*, J.J. Stewart* and B.A. Watkins*. 2000. Effects of conjugated linoleic aci. 1. Fatty acid modification of yolks and neonatal fatty acid metabolism. Poultry Sci. 79: 817-821.

37)        Latour*, M.A., R.A. Meunier*, A.A. Devitt*, J.J. Stewart* and B.A. Watkins*. 2000. Effects of conjugated linoleic acid. 2. Embryonic and neonatal growth and circulating lipids. Poultry Sci. 79:822-826.

38)        Peebles*, E.D., C.D. Zumwalt*, S.M. Doyle*, P.D. Gerrard*, M.A. Latour*, C.R. Boyle and T.W. Smith. 2000. Effects of dietary fat type and level on broiler breeder performance. Poultry Sci. 79:629-639.

39)        Peebles*, E.D., C.D. Zumwalt*, S.M. Doyle*, P.D. Gerrard*, M.A. Latour*, C.R. Boyle and T.W. Smith*.  2000.  Effects of breeder age and dietary fat source and level on broiler hatching egg characteristics. Poultry Sci. 79:698-704.

40)        Latour*, M.A., R.A. Meunier*, D. Huber* and K. Stallings*. 2000. Ammoniated broiler diets reduce fecal phosphorus excretion. Journal of Applied Animal  Research 18:91-95.

 41)        Latour*, M.A., R.A. Meunier*, C.M. Braun*, J.M. Eggert* and A.P. Schinckel.  2000.  Conjugated linoleic acid enriched swine fat alters the growth profile and VLDL composition of Sprague Dawley rats.  Baltic Journal of Laboratory Animal Science 10:221-226.

42)        Latour*, M. A., E.D. Peebles*, S.M. Doyle, and T. Pansky, 2001.  Effects of broiler breeder hen age and dietary fat intake on circulating serum lipids.  Journal of Applied Animal Research 19:73-84.

43)        Braun*, C.M., J. M. Burgess*, and M.A. Latour*, 2001.  Liver lipid accumulation in duck embryos and hatchlings changes with parental age.  Biology of the Neonate (in press).

44)        Braun*, C.M., N. Frank*, and M.A. Latour*, 2001.  Changes in circulating lipids in duck embryos and newly hatched ducklings from different age parents (submitted to Biology of the Neonate).

45)        Peebles*, E.D., S.M. Doyle*, C.D. Zumwalt*, P.D. Gerrard*, M.A. Latour*, and C.R. Boyle*, 2001.  Breeder age influences embryogenesis in broiler hatching eggs (submitted Poultry Science).

46)        Doyle*, S.M., M. Gray*, P.D. Kregor*, P. A. Cole*, E. Herrington*, E.D. Peebles*, M.A. Latour*, and J.L. Hughes, 2001.  Radiological procedures for assessment of high-energy fractures of the acetabulum (submitted Radiology).

47)        Neuman*, S.L., J.I. Orban*, T.L. Lin*, M.A. Latour*, and P.Y. Hester*, 2001.  The effects of dietary ascorbic acid on semen traits and testis histology of male turkey breeders (submitted to Poultry Science).

Book Chapter:

1)            Watkins*, B.A., A.A. Devitta*, L. Yu* and M.A. Latour*. 1999. Biological activities of conjugated linoleic acid and designer eggs (Chapter 14).  IN: Egg Nutrition and Biotechnology, 2nd Edition. pp. 181-195.

2)            Watkins, BA, Devitt, AA, Yu, L and Latour, MA., 2001.  Biological activities of conjugated linoleic acids and designer eggs.  Egg nutrition and Newly Emgerging Ovo-Biotechnology 2nd Ed.  J.S. Sim, S. Nakai and W. Guenter editors. CABI Publishing, UK. (IN PRESS).